Start Submission Become a Reviewer

Reading: Impact of coconut and palm oils on cardio-metabolic risk factors: study protocol for a human...

Download

A- A+
Alt. Display

Original Articles

Impact of coconut and palm oils on cardio-metabolic risk factors: study protocol for a human study

Authors:

Hasinthi Swarnamali ,

University of Colombo, Colombo, LK
About Hasinthi
Health and Wellness Unit, Faculty of Medicine
X close

Priyanga Ranasinghe,

University of Colombo, Colombo, LK
About Priyanga
Department of Pharmacology, Faculty of Medicine
X close

Ranil Jayawardena

University of Colombo, Colombo, LK
About Ranil

Department of Physiology, Faculty of Medicine

Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia

X close

Abstract

Background

Although the traditional Sri Lankan diet is low in fat content, the incidenceof cardiovascular diseases is high. This probably correlate with high saturated fat and cholesterol intake. This study is to investigate the impact of coconut oil and palm oil as cooking oil media, which are the primary dietary saturated fat sources among Sri Lankans, on cardio-metabolic risk factors.

 

Methods

The study will be conducted as a sequential feeding clinical trial. The study has been approved by the Ethics Review Committee of Faculty of Medicine, University of Colombo (EC/19/046). A total of 40 healthy adults from the general community will be recruited. The study will be divided into two feeding periods of 8 weeks each for coconut oil and palm oil. Participants will be provided the first test oil for the first feeding period and then, the second test oil will be continued for another 8 weeks keeping 4 weeks of washout period in between. The anthropometric and biochemical investigations will be done at the beginning of the first feeding period, at the end of the first feeding period (8th week), at the beginning of the second feeding period (12th week), and at the end of the second feeding period (20th week) of the study. The primary outcome index will be the difference in the change in serum low-density lipoprotein cholesterol concentration between the two feeding periods. Secondary outcome measures include the serum concentrations of, total and high-density lipoprotein cholesterol (TC and HDL-C), TC/HDL-C ratio, triglycerides, very low-density lipoprotein cholesterol, fasting plasma glucose, liver enzymes, anthropometry, blood pressure, dietary and physical activity assessment. Data will be analyzed using SPSS v 22.

 

Discussion

The expected outcome of the study is an improved understanding of the differences in cardiometabolic risk factors between the consumption of coconut oil and palm oil.
How to Cite: Swarnamali, H., Ranasinghe, P. and Jayawardena, R., 2020. Impact of coconut and palm oils on cardio-metabolic risk factors: study protocol for a human study. Ceylon Journal of Medical Science, 57(1), pp.19–27. DOI: http://doi.org/10.4038/cjms.v57i1.4969
Published on 28 Dec 2020.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus