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Original Articles

The role of lower genital tract microflora and antenatal maternal risk factors in preterm labour

Authors:

R. J. Fernando ,

University of Ruhuna, Galle, LK
About R. J.
Departments of Obstertics and Gynaecology
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I. M. R. Goonewardene,

University of Ruhuna, Galle, LK
About I. M. R.
Departments of Obstertics and Gynaecology
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A. Nagahawatte,

University of Ruhuna, Galle, LK
About A.
Dept. of Microbiology
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S. Fernando

University of Ruhuna, Galle, LK
About S.
Dept. of Microbiology
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Abstract

Objective: To determine the role of lower genital tract microflora and antenatal maternal risk factors in pre term labour (PTL).

Design: A prospective cohort study.

Setting: University obstetric unit and the Department of Microbiology, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.

Subjects: Two hundred and one pregnant women with periods of gestation (POG) less than 25 weeks, presenting for antenatal care.

Method: Antenatal maternal risk factors for PTL were documented and swabs from posterior vaginal fornix and endocervical canal were obtained at the booking visit and at a POG of 32 weeks. The microbiological findings at booking and at a POG of 32 weeks, and the antenatal maternal risk factors in each subject were correlated with the occurrence of PTL.

Results and Conclusions: Colonisation of the lower genital tract with probable anaerobic gram negative bacilli at booking and possibly at a POG of 32 weeks was a high risk factor for the occurrence of PTL. Teenage and low socioeconomic status were also high risk factors associated with PTL. Current multiple pregnancy showed a possible association with the occurrence of PTL.

How to Cite: Fernando, R.J. et al., (2001). The role of lower genital tract microflora and antenatal maternal risk factors in preterm labour. Ceylon Journal of Medical Science. 44(2), pp.41–51. DOI: http://doi.org/10.4038/cjms.v44i2.4866
Published on 29 Dec 2001.
Peer Reviewed

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